Custom-compounded estriol 0.3% with vitamin C 1% and hyaluronic acid 0.5% in a 30g pump. Supports skin hydration, texture, and tone as estrogen levels decline.
The Difference
$50 consult + ~$75 pharmacy = ~$125 one-time. A 30g pump typically lasts 2–4 months. Reorder on your schedule, not an auto-refill calendar.
Typical online services for compounded estriol skincare charge $33–$50 per month on auto-refill, adding up to $400–$600 per year even if you don't need that much cream.
Range reflects common direct-to-consumer pricing for comparable services as of 2026.
What It Does
As estrogen declines, the skin loses collagen, hydration, and elasticity faster than general moisturizers can replace. Topical estriol supports skin thickness and elasticity during and after menopause. Combined with vitamin C (antioxidant brightening) and hyaluronic acid (deep hydration), this custom-compounded cream supports healthy, resilient skin.
Thin, Crepey Skin. Estrogen loss accelerates collagen breakdown. Estriol supports dermal thickness and elasticity.
Persistent Dryness. Aging skin retains less moisture. Hyaluronic acid (up to 1,000× its weight in water) restores hydration.
Uneven Tone. Vitamin C brightens, evens tone, and protects against environmental damage.
Overall Quality. Many patients report firmer, smoother skin within 8–12 weeks of consistent nightly use.
The weakest naturally occurring estrogen, with primarily local action. Supports skin thickness and elasticity as estrogen levels decline.
Antioxidant that brightens skin tone and offers environmental protection against free radical damage.
Humectant that draws water into the skin, restoring hydration and improving surface plumpness.
30 grams with one refill included. Typical use: 1 pump nightly lasts ~4 months, 2 pumps nightly lasts ~2 months.
Secure questionnaire covering medical and skin history. 5–10 minutes.
Licensed clinician reviews your request. Typically 1–2 business days.
Sent to the compounding pharmacy. You pay the pharmacy directly (~$75) separately from our $50 service fee.
This cream is custom-compounded by a licensed compounding pharmacy based on individual prescriptions. Compounded medications are not FDA-approved as commercial products. Estriol is a prescription ingredient; we evaluate each request individually.
We do not prescribe to patients with active or recent estrogen-sensitive cancers, during pregnancy or breastfeeding, or in patients under 18. Please disclose your medical history fully during intake.
Important Safety Information
See our full prescribing and safety terms, including the off-label prescribing disclosure and compounded-medications disclosure.
$50 service fee. Custom-compounded estriol + vitamin C + hyaluronic acid. Available in 16 states.
131 N Washington Street, Suite A · Papillion, NE 68046 · Info@midwestmindandbodyhealthcare.com
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