Prescription Tretinoin Cream

Prescription tretinoin, without the office visit.

Prescription-strength tretinoin for smoother skin texture, reduced fine lines, and acne. Custom-compounded formulations. Clinician-reviewed online. No appointment needed.

Low Cost
$125
total, first fill
no subscription
Quick
1–2
business days
clinician review
Easy
0
appointments
online intake
How It Works
$50 service fee · Pharmacy cost separate · 1–2 business day review · 16 states

The Difference

Pay once. No subscription. No auto-refill.

$50 consult + ~$75 pharmacy = ~$125 one-time. Reorder only when you're ready. No recurring charges.

For Comparison

Typical online prescription tretinoin services charge $30–$50 per month on auto-refill subscriptions. Over a year, that's roughly $350–$550 for the same medication.

Range reflects common direct-to-consumer pricing for comparable services as of 2026.

What It Treats

Tretinoin is the gold-standard prescription retinoid.

Tretinoin is a topical vitamin A derivative that accelerates cell turnover, boosts collagen production, and unclogs pores. It is one of the most studied skincare prescriptions available, used for decades by dermatologists for both anti-aging and acne.

Fine Lines & Wrinkles. Stimulates collagen synthesis to soften lines around the eyes, mouth, and forehead. Most patients see improvement by week 12.

Acne & Breakouts. Prevents pore clogging, reduces inflammation, and clears existing acne. Effective for both hormonal and comedonal acne.

Uneven Skin Tone. Fades dark spots, post-acne marks, and hyperpigmentation through accelerated cell turnover.

Rough Texture. Smooths surface texture, minimizes pore appearance, and restores a refined skin feel.

Formulations Available

Custom-compounded for your skin.

01
🌱

Face: Sensitive (0.025%)

Tretinoin 0.025% with niacinamide and hyaluronic acid. Best for first-time retinoid users and reactive skin types. Gentler introduction with less purging.

$50 service fee
+ pharmacy cost
02
⚖️

Face: Normal (0.05%)

Tretinoin 0.05% for patients with established retinoid tolerance seeking moderate anti-aging and acne results. Our most commonly prescribed strength.

$50 service fee
+ pharmacy cost
03
🔥

Face: Advanced (0.1%)

Tretinoin 0.1% is the highest-strength topical option. For experienced retinoid users seeking maximum anti-aging effects. Requires tolerance first.

$50 service fee
+ pharmacy cost
04
👗

Neck & Chest

Formulated with adjusted concentrations appropriate for the more delicate skin of the neck and chest. Addresses crepey texture and sun damage in these often-neglected areas.

$50 service fee
+ pharmacy cost
How to Get Your Prescription

Three steps. No appointment. No waiting room.

1

Complete Online Intake

Answer secure health questionnaire covering skin history, current routine, and medical history. Takes 5–10 minutes.

2

Clinician Reviews

A licensed clinician reviews your request, typically within 1–2 business days. If anything needs clarification, we reach out via secure messaging.

3

Prescription Sent

If approved, your prescription is sent to the compounding pharmacy. You pay the pharmacy directly for the medication, separate from our $50 service fee.

What to Expect

Real results take
real time.

Tretinoin works at the cellular level. Meaningful visible improvement typically emerges between 8 and 12 weeks with consistent nightly use. Most prescriptions include refills to cover 9–12 months of use before reassessment.

Initial side effects are common and normal: redness, dryness, mild peeling, and occasional purging typically resolve within 4–6 weeks as your skin adjusts. Gradual introduction (2–3 nights per week initially) reduces irritation dramatically.

Daily SPF is non-negotiable. Tretinoin increases photosensitivity. Without consistent sunscreen use, you will undo the work tretinoin is doing. We discuss this during intake.

01

Nightly Application

Apply pea-sized amount to clean, dry face after cleansing. Introduce slowly to reduce irritation.

02

Daily Sunscreen

SPF 30+ every morning is mandatory. Tretinoin makes skin more photosensitive.

03

Gentle Routine

Avoid other active exfoliants (AHAs, BHAs, strong vitamin C) while adjusting to tretinoin.

04

Not in Pregnancy

Tretinoin is contraindicated during pregnancy and breastfeeding. Please disclose in intake.

About Custom-Compounded Tretinoin

Our tretinoin formulations are custom-compounded by a licensed compounding pharmacy based on individual prescriptions and clinical judgment. Compounded medications are not FDA-approved as commercial products.

Tretinoin is contraindicated during pregnancy, breastfeeding, and while planning pregnancy. We do not prescribe to patients under 18. If you have eczema, rosacea, or a history of retinoid hypersensitivity, please disclose this during intake.

Other Online Prescriptions

Explore other products

Important Safety Information

Before starting prescription tretinoin, please read.

See our full prescribing and safety terms and our compounded-medications disclosure.

Common Questions

Tretinoin, answered.

$50 service fee per prescription. The compounding pharmacy typically charges around $75 for a 30g tube, with three refills included. One tube lasts 8–12 weeks depending on coverage area.
First-time retinoid users typically start at 0.025%. Patients with established tolerance can start at 0.05%. The 0.1% strength is for experienced users. We recommend the right strength during intake based on your skin history.
Meaningful improvement typically emerges between 8 and 12 weeks with consistent nightly use. Smoother texture often comes first; fine line improvement takes longer.
Initial redness, dryness, mild peeling, and temporary acne "purging" are common in the first 4–6 weeks as skin adjusts. Gradual introduction (starting 2–3 nights weekly) reduces irritation significantly.
No. Tretinoin is contraindicated during pregnancy, breastfeeding, and while actively planning pregnancy. Please disclose this in the intake; we will not prescribe if you are pregnant or breastfeeding.
Yes, this is not optional. Tretinoin increases photosensitivity. Daily SPF 30+ is required; without it, you will undo the anti-aging work tretinoin is doing.

Ready to start
your tretinoin routine?

$50 service fee. Clinician-reviewed. Available in 16 states. Prescriptions typically reviewed within 1–2 business days.

131 N Washington Street, Suite A · Papillion, NE 68046 · Info@midwestmindandbodyhealthcare.com

Please do not send protected health information (PHI) by email. For secure communication about your care, use our patient portal after booking.

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